Toyoaki Murohara Selected Research

Systemic carnitine deficiency

9/2007	Pressure overload-induced cardiomyopathy in heterozygous carrier mice of carnitine transporter gene mutation.
6/2006	Combined therapy with PPARalpha agonist and L-carnitine rescues lipotoxic cardiomyopathy due to systemic carnitine deficiency.
11/2005	Dietary fish oil attenuates cardiac hypertrophy in lipotoxic cardiomyopathy due to systemic carnitine deficiency.
6/2003	Impact of alpha-tocopherol on cardiac hypertrophy due to energy metabolism disorder: the involvement of 1,2-diacylglycerol.

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Toyoaki Murohara Research Topics

Disease

102	Heart Failure 11/2022 - 11/2004
96	Cardiovascular Diseases (Cardiovascular Disease) 08/2022 - 10/2002
75	Myocardial Infarction 07/2022 - 02/2004
68	Atrial Fibrillation 03/2022 - 10/2004
54	Ischemia 01/2022 - 03/2002
51	Inflammation (Inflammations) 03/2022 - 01/2004
46	Hypertension (High Blood Pressure) 01/2022 - 11/2003
42	Fibrosis (Cirrhosis) 01/2022 - 02/2004
41	Coronary Artery Disease (Coronary Atherosclerosis) 07/2022 - 12/2003
35	Atherosclerosis 01/2020 - 11/2003
27	Obesity 01/2018 - 09/2006
25	Chronic Renal Insufficiency 01/2022 - 07/2009
24	Thrombosis (Thrombus) 07/2022 - 12/2002
23	Hypertrophy 01/2022 - 07/2005
23	Left Ventricular Dysfunction 01/2021 - 02/2004
21	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 04/2006
20	ST Elevation Myocardial Infarction 09/2022 - 08/2005
20	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 12/2021 - 11/2004
20	Insulin Resistance 01/2018 - 12/2004
19	Body Weight (Weight, Body) 01/2022 - 06/2003
19	Hypoxia (Hypoxemia) 12/2021 - 01/2003
19	Hemorrhage 06/2021 - 07/2012
19	Type 2 Diabetes Mellitus (MODY) 01/2020 - 05/2007
18	Diabetes Mellitus 05/2019 - 01/2004
16	Stroke (Strokes) 09/2022 - 08/2010
16	Myocardial Ischemia (Ischemic Heart Diseases) 12/2021 - 10/2005
16	Atherosclerotic Plaque (Atheroma) 01/2020 - 01/2008
15	Acute Coronary Syndrome 01/2021 - 11/2004
15	Cardiomegaly (Heart Hypertrophy) 11/2019 - 06/2003
14	Neoplasms (Cancer) 09/2022 - 07/2003
13	Chronic Limb-Threatening Ischemia 11/2022 - 09/2006
13	Death (Near-Death Experience) 06/2022 - 11/2004
13	Peripheral Arterial Disease 04/2022 - 07/2008
13	Infarction (Infarctions) 07/2020 - 02/2004
11	Glucose Intolerance 08/2017 - 03/2004
10	Ventricular Tachycardia 10/2022 - 07/2008
10	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 01/2021 - 07/2003
10	Neointima 12/2019 - 01/2005
9	Reperfusion Injury 12/2018 - 02/2006
9	Stable Angina 02/2017 - 03/2006
8	Cardiogenic Shock 07/2022 - 01/2020
8	Cardiac Arrhythmias (Arrythmia) 01/2021 - 08/2009
8	Vascular Diseases (Vascular Disease) 01/2020 - 03/2006
8	Hypercholesterolemia 01/2018 - 07/2003
7	Myocarditis (Carditis) 05/2022 - 07/2015
7	Pulmonary Arterial Hypertension 04/2022 - 06/2014
7	Pathologic Constriction (Stenosis) 01/2022 - 01/2004
7	Hyperuricemia 01/2020 - 10/2003

Drug/Important Bio-Agent (IBA)

40	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2003
37	AdiponectinIBA 10/2018 - 04/2006
35	LipidsIBA 01/2022 - 06/2003
27	SaltsIBA 01/2022 - 10/2005
23	omega-Chloroacetophenone (Mace)IBA 07/2022 - 11/2004
20	AdipokinesIBA 10/2017 - 05/2011
19	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 01/2003
17	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 08/2006
17	AnticoagulantsIBA 04/2021 - 06/2005
17	Angiotensin Receptor AntagonistsIBA 07/2020 - 12/2003
16	Biomarkers (Surrogate Marker)IBA 03/2022 - 07/2009
16	HDL CholesterolIBA 01/2020 - 06/2007
15	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 06/2006
15	C-Reactive ProteinIBA 01/2022 - 04/2006
13	Matrix Metalloproteinases (MMPs)IBA 01/2022 - 02/2004
12	Angiotensin IIIBA 01/2022 - 03/2002
11	Brain Natriuretic Peptide (Natrecor)FDA Link 08/2022 - 06/2006
11	Messenger RNA (mRNA)IBA 07/2022 - 02/2004
11	ApolipoproteinsIBA 01/2022 - 10/2003
11	Oxygen (Dioxygen)IBA 12/2021 - 08/2002
11	oxidized low density lipoproteinIBA 01/2019 - 09/2004
10	CytokinesIBA 10/2020 - 02/2004
9	Indicators and Reagents (Reagents)IBA 11/2022 - 10/2008
9	Warfarin (Coumadin)FDA LinkGeneric 01/2020 - 02/2013
9	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 05/2017 - 02/2008
9	Antihypertensive Agents (Antihypertensives)IBA 01/2016 - 04/2006
9	MetalsIBA 10/2013 - 03/2006
9	Sirolimus (Rapamycin)FDA Link 10/2013 - 11/2006
8	Pharmaceutical PreparationsIBA 04/2022 - 07/2003
8	Serum AlbuminIBA 01/2021 - 01/2012
8	Dobutamine FDA LinkGeneric 01/2020 - 11/2008
8	erucylphosphocholineIBA 11/2019 - 01/2003
8	LDL CholesterolIBA 01/2019 - 12/2010
8	pitavastatin (itavastatin)FDA Link 01/2018 - 06/2006
8	Insulin (Novolin)FDA Link 01/2018 - 12/2004
8	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2015 - 11/2006
7	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 12/2021 - 05/2010
7	Uric Acid (Urate)IBA 01/2020 - 04/2009

Therapy/Procedure

78	Therapeutics 04/2022 - 02/2006
65	Percutaneous Coronary Intervention 09/2022 - 11/2004
37	Stents 07/2022 - 01/2004
37	Catheter Ablation 03/2022 - 03/2006
32	Renal Dialysis (Hemodialysis) 07/2022 - 08/2006
14	Cardiac Resynchronization Therapy 10/2022 - 10/2006
14	Catheters 01/2022 - 07/2004
14	Drug-Eluting Stents 09/2020 - 12/2009
10	Patient Readmission 06/2022 - 08/2005
10	Extracorporeal Membrane Oxygenation 03/2022 - 01/2018
9	Ligation 01/2019 - 02/2004
8	Surgical Amputation (Amputations) 11/2022 - 11/2008
8	Heart-Assist Devices 09/2022 - 02/2020
8	Transplantation 09/2014 - 03/2002